Deneb IV is the name of a planet in multiple works of science fiction.
- Deneb IV - "Encounter at Farpoint, Part I" and "Encounter at Farpoint, Part II," Star Trek: The Next Generation Episode 1, Season 1, 9-28-1987
- Babylon 5 universe
- "The Mystery of Deneb IV," a short story by Robert Silverberg in Fantastic February 1957
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